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MessagePosté le: Ven 20 Mai - 03:24 (2016)    Sujet du message: D?y%@Tr?/%T? K?_ H?C S? Tar-get= Répondre en citant




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.Page,,1,,of,,1You,,are,,here:,,NCBI,,>,,Literature,,>,,PubMed,,Write,,to,,the,,Help,,Desk,,You,,,may,,,have,,,mistyped,,,the,,,address,,,or,,,the,,,page,,,may,,,have,,,moved.Permissions,,,in,,,this,,,forum:You,,,cannot,,,reply,,,to,,,topics,,,in,,,this,,,forumMarvel/DC,,,Legends::RP,,,Area::TenaraMarvel/DC,,,Legends::RP,,,Area::TenaraSimilar,,,,topicsMean,,,,age,,,,was,,,,63,,,,(SD,,,,11),,,,yearsWarning:,,The,,NCBI,,web,,site,,requires,,JavaScript,,to,,functionPrimary,,,,events,,,,were,,,,all,,,,recurrent,,,,strokes,,,,,myocardial,,,,infarction,,,,,or,,,,vascular,,,,deathdoi:,,10.1016/S0140-6736(13)60852-1Jump,,,to:Select,,,a,,,forum--General--Rules!--RP,,,Area--Yarra--Around,,,the,,,Island--Apartments--Main,,,HQ--Tenara--Main,,,HQ--Apartment--North,,,America--South,,,America--Europe--Asia--Africa--OtherSimple,,NCBI,,Directory,,Getting,,Started,,NCBI,,Education,,NCBI,,Help,,Manual,,NCBI,,Handbook,,Training,,&,,Tutorials,,Submit,,Data,,Resources,,Chemicals,,&,,BioassaysData,,&,,SoftwareDNA,,&,,RNADomains,,&,,StructuresGenes,,&,,ExpressionGenetics,,&,,MedicineGenomes,,&,,MapsHomologyLiteratureProteinsSequence,,AnalysisTaxonomyVariation,,Popular,,PubMed,,Bookshelf,,PubMed,,Central,,PubMed,,Health,,BLAST,,Nucleotide,,Genome,,SNP,,Gene,,Protein,,PubChem,,Featured,,Genetic,,Testing,,Registry,,PubMed,,Health,,GenBank,,Reference,,Sequences,,Gene,,Expression,,Omnibus,,Map,,Viewer,,Human,,Genome,,Mouse,,Genome,,Influenza,,Virus,,Primer-BLAST,,Sequence,,Read,,Archive,,NCBI,,Information,,About,,NCBI,,Research,,at,,NCBI,,NCBI,,News,,NCBI,,FTP,,Site,,NCBI,,on,,Facebook,,NCBI,,on,,Twitter,,NCBI,,on,,YouTube,,External,,linkHR=hazard,,ratio.Effects,,of,,Blood,,Pressure,,Targets,,in,,Patients,,with,,Recent,,Lacunar,,StrokeLancetTreatment-related,,,,serious,,,,adverse,,,,events,,,,were,,,,infrequent.INTERPRETATION:,,,,Although,,,,the,,,,reduction,,,,in,,,,stroke,,,,was,,,,not,,,,significant,,,,,our,,,,results,,,,support,,,,that,,,,in,,,,patients,,,,with,,,,recent,,,,lacunar,,,,stroke,,,,,the,,,,use,,,,of,,,,a,,,,systolic-blood-pressure,,,,target,,,,of,,,,less,,,,than,,,,130,,,,mm,,,,Hg,,,,is,,,,likely,,,,to,,,,be,,,,beneficial.FUNDING:,,,,National,,,,Institutes,,,,of,,,,Health-National,,,,Institute,,,,of,,,,Neurological,,,,Disorders,,,,and,,,,Stroke,,,,(NIH-NINDS).Copyright,,,,,,,,2013,,,,Elsevier,,,,LtdAll,,,rights,,,reserved.Comment,,,inAn,,,optimum,,,blood,,,pressure,,,target,,,after,,,lacunar,,,stroke?,,,[LancetThe,,,,page,,,,you,,,,were,,,,looking,,,,for,,,,doesn't,,,,exist2014]Lessons,,from,,the,,SPS3,,trialSupplemental,,,,Content,,,,Full,,,,text,,,,links,,,,Result,,,Filters,,,The,,,rate,,,of,,,intracerebral,,,haemorrhage,,,was,,,reduced,,,significantly,,,(037,,,,015-095,,,,p=003)Patients,,,,were,,,,recruited,,,,between,,,,March,,,,,2003,,,,,and,,,,April,,,,,2011,,,,,and,,,,randomly,,,,assigned,,,,,according,,,,to,,,,a,,,,two-by-two,,,,multifactorial,,,,design,,,,,to,,,,a,,,,systolic-blood-pressure,,,,target,,,,of,,,,130-149,,,,mm,,,,Hg,,,,or,,,,less,,,,than,,,,130,,,,mm,,,,HgNon-significant,,rate,,reductions,,were,,seen,,for,,all,,stroke,,(hazard,,ratio,,081,,,95%,,CI,,064-103,,,p=008),,,disabling,,or,,fatal,,stroke,,(081,,,053-123,,,p=032),,,and,,the,,composite,,outcome,,of,,myocardial,,infarction,,or,,vascular,,death,,(084,,,068-104,,,p=032),,with,,the,,lower,,target;382(9891):507-515.Publication,,Types,,,MeSH,,Terms,,,Substances,,,Secondary,,Source,,ID,,,Grant,,SupportPublication,,TypesMulticenter,,StudyRandomized,,Controlled,,TrialResearch,,Support,,,N.I.H.,,,ExtramuralMeSH,,TermsAntihypertensive,,Agents/therapeutic,,use*Blood,,Pressure/drug,,effectsCerebral,,Hemorrhage/prevention,,&,,controlFemaleHumansHypertension/physiopathologyHypertension/prevention,,&,,control*MaleMiddle,,AgedSecondary,,PreventionStroke,,,Lacunar/physiopathologyStroke,,,Lacunar/prevention,,&,,control*SystoleTime-to-TreatmentTreatment,,OutcomeSubstancesAntihypertensive,,AgentsSecondary,,Source,,IDClinicalTrials.gov/NCT00059306Grant,,SupportU01,,NS038529/NS/NINDS,,NIH,,HHS/United,,StatesU01NS038529/NS/NINDS,,NIH,,HHS/United,,StatesUL1,,TR000439/TR/NCATS,,NIH,,HHS/United,,StatesLinkOut,,-,,more,,resourcesFull,,Text,,SourcesElsevier,,ScienceClinical,,KeyEurope,,PubMed,,Central,,-,,Author,,ManuscriptPubMed,,Central,,-,,Author,,ManuscriptPubMed,,Central,,Canada,,-,,Author,,ManuscriptMedicalClinicalTrials.govBlood,,Pressure,,Medicines,,-,,MedlinePlus,,Health,,InformationHigh,,Blood,,Pressure,,-,,MedlinePlus,,Health,,InformationPubMed,,Commons,,home,,PubMed,,Commons,,0,,commentsHow,,to,,join,,PubMed,,CommonsHow,,to,,cite,,this,,comment:,,AbstractFormatSummarySummary,,,,(text)AbstractAbstract,,,,(text)MEDLINEXMLPMID,,,,ListApplySend,,,,to:Choose,,,,DestinationFileClipboardCollectionsE-mailOrderMy,,,,BibliographyCitation,,,,managerFormatSummary,,,,(text)Abstract,,,,(text)MEDLINEXMLPMID,,,,ListCSVCreate,,,,File1,,,,selected,,,,item:,,,,23726159FormatSummarySummary,,,,(text)AbstractAbstract,,,,(text)MEDLINEXMLPMID,,,,ListMeSH,,,,and,,,,Other,,,,DataE-mailSubjectAdditional,,,,textE-mailDidn't,,,,get,,,,the,,,,message?,,,,Find,,,,out,,,,why.Add,,,,to,,,,ClipboardAdd,,,,to,,,,CollectionsOrder,,,,articlesAdd,,,,to,,,,My,,,,BibliographyGenerate,,,,a,,,,file,,,,for,,,,use,,,,with,,,,external,,,,citation,,,,management,,,,software.Create,,,,File,,,,See,,,,comment,,,,in,,,,PubMed,,,,Commons,,,,belowLancetMarvel/DC,,,,Legends::RP,,,,Area::TenaraShareCoffey,,,,C,,,S,,,[aded]This,,,,study,,,,is,,,,registered,,,,with,,,,ClinicalTrials.gov,,,,,number,,,,NCT,,,,00059306.FINDINGS:,,,,3020,,,,enrolled,,,,patients,,,,,1519,,,,in,,,,the,,,,higher-target,,,,group,,,,and,,,,1501,,,,in,,,,the,,,,lower-target,,,,group,,,,,were,,,,followed,,,,up,,,,for,,,,a,,,,mean,,,,of,,,,37,,,,(SD,,,,20),,,,years2014]PMID:,,,23726159,,,[PubMed,,,-,,,indexed,,,for,,,MEDLINE],,,PMCID:,,,PMC3979302,,,Free,,,PMC,,,ArticleShareImages,,,from,,,this,,,publication.See,,,all,,,images,,,(4)Free,,,textFigure,,,1Systolic,,,blood,,,pressure,,,by,,,treatment,,,group.Effects,,,of,,,Blood,,,Pressure,,,Targets,,,in,,,Patients,,,with,,,Recent,,,Lacunar,,,StrokeLancet;382(9891):507-515.Figure,,,3Primary,,,outcome,,,assessed,,,by,,,demographic,,,and,,,clinical,,,subgroupsThe,,primary,,endpoint,,was,,reduction,,in,,all,,stroke,,(including,,ischaemic,,strokes,,and,,intracranial,,haemorrhages)NCBISkip,,,to,,,main,,,contentSkip,,,to,,,navigationResourcesAll,,,ResourcesChemicals,,,&,,,BioassaysBioSystemsPubChem,,,BioAssayPubChem,,,CompoundPubChem,,,Structure,,,SearchPubChem,,,SubstanceAll,,,Chemicals,,,&,,,Bioassays,,,Resources.DNA,,,&,,,RNABLAST,,,(Basic,,,Local,,,Alignment,,,Search,,,Tool)BLAST,,,(Stand-alone)E-UtilitiesGenBankGenBank:,,,BankItGenBank:,,,SequinGenBank:,,,tbl2asnGenome,,,WorkbenchInfluenza,,,VirusNucleotide,,,DatabasePopSetPrimer-BLASTProSplignReference,,,Sequence,,,(RefSeq)RefSeqGeneSequence,,,Read,,,Archive,,,(SRA)SplignTrace,,,ArchiveUniGeneAll,,,DNA,,,&,,,RNA,,,Resources.Data,,,&,,,SoftwareBLAST,,,(Basic,,,Local,,,Alignment,,,Search,,,Tool)BLAST,,,(Stand-alone)Cn3DConserved,,,Domain,,,Search,,,Service,,,(CD,,,Search)E-UtilitiesGenBank:,,,BankItGenBank:,,,SequinGenBank:,,,tbl2asnGenome,,,ProtMapGenome,,,WorkbenchPrimer-BLASTProSplignPubChem,,,Structure,,,SearchSNP,,,Submission,,,ToolSplignVector,,,Alignment,,,Search,,,Tool,,,(VAST)All,,,Data,,,&,,,Software,,,Resources.Domains,,,&,,,StructuresBioSystemsCn3DConserved,,,Domain,,,Database,,,(CDD)Conserved,,,Domain,,,Search,,,Service,,,(CD,,,Search)Structure,,,(Molecular,,,Modeling,,,Database)Vector,,,Alignment,,,Search,,,Tool,,,(VAST)All,,,Domains,,,&,,,Structures,,,Resources.Genes,,,&,,,ExpressionBioSystemsDatabase,,,of,,,Genotypes,,,and,,,Phenotypes,,,(dbGaP)E-UtilitiesGeneGene,,,Expression,,,Omnibus,,,(GEO),,,Database,,,Gene,,,Expression,,,Omnibus,,,(GEO),,,DatasetsGene,,,Expression,,,Omnibus,,,(GEO),,,ProfilesGenome,,,WorkbenchHomoloGeneMap,,,ViewerOnline,,,Mendelian,,,Inheritance,,,in,,,Man,,,(OMIM)RefSeqGeneUniGeneAll,,,Genes,,,&,,,Expression,,,Resources.Genetics,,,&,,,MedicineBookshelfDatabase,,,of,,,Genotypes,,,and,,,Phenotypes,,,(dbGaP)Genetic,,,Testing,,,RegistryInfluenza,,,VirusMap,,,ViewerOnline,,,Mendelian,,,Inheritance,,,in,,,Man,,,(OMIM)PubMedPubMed,,,Central,,,(PMC)PubMed,,,Clinical,,,QueriesRefSeqGeneAll,,,Genetics,,,&,,,Medicine,,,Resources.Genomes,,,&,,,MapsDatabase,,,of,,,Genomic,,,Structural,,,Variation,,,(dbVar)GenBank:,,,tbl2asnGenomeGenome,,,ProjectGenome,,,ProtMapGenome,,,WorkbenchInfluenza,,,VirusMap,,,ViewerNucleotide,,,DatabasePopSetProSplignSequence,,,Read,,,Archive,,,(SRA)SplignTrace,,,ArchiveAll,,,Genomes,,,&,,,Maps,,,Resources.HomologyBLAST,,,(Basic,,,Local,,,Alignment,,,Search,,,Tool)BLAST,,,(Stand-alone)BLAST,,,Link,,,(BLink)Conserved,,,Domain,,,Database,,,(CDD)Conserved,,,Domain,,,Search,,,Service,,,(CD,,,Search)Genome,,,ProtMapHomoloGeneProtein,,,ClustersAll,,,Homology,,,Resources.LiteratureBookshelfE-UtilitiesJournals,,,in,,,NCBI,,,DatabasesMeSH,,,DatabaseNCBI,,,HandbookNCBI,,,Help,,,ManualNCBI,,,NewsPubMedPubMed,,,Central,,,(PMC)PubMed,,,Clinical,,,QueriesPubMed,,,HealthAll,,,Literature,,,Resources.ProteinsBioSystemsBLAST,,,(Basic,,,Local,,,Alignment,,,Search,,,Tool)BLAST,,,(Stand-alone)BLAST,,,Link,,,(BLink)Conserved,,,Domain,,,Database,,,(CDD)Conserved,,,Domain,,,Search,,,Service,,,(CD,,,Search)E-UtilitiesProSplignProtein,,,ClustersProtein,,,DatabaseReference,,,Sequence,,,(RefSeq)All,,,Proteins,,,Resources.Sequence,,,AnalysisBLAST,,,(Basic,,,Local,,,Alignment,,,Search,,,Tool)BLAST,,,(Stand-alone)BLAST,,,Link,,,(BLink)Conserved,,,Domain,,,Search,,,Service,,,(CD,,,Search)Genome,,,ProtMapGenome,,,WorkbenchInfluenza,,,VirusPrimer-BLASTProSplignSplignAll,,,Sequence,,,Analysis,,,Resources.TaxonomyTaxonomyTaxonomy,,,BrowserTaxonomy,,,Common,,,TreeAll,,,Taxonomy,,,Resources.Training,,,&,,,TutorialsNCBI,,,Education,,,PageNCBI,,,HandbookNCBI,,,Help,,,ManualNCBI,,,NewsAll,,,Training,,,&,,,Tutorials,,,Resources.VariationDatabase,,,of,,,Genomic,,,Structural,,,Variation,,,(dbVar)Database,,,of,,,Genotypes,,,and,,,Phenotypes,,,(dbGaP)Database,,,of,,,Single,,,Nucleotide,,,Polymorphisms,,,(dbSNP)SNP,,,Submission,,,ToolAll,,,Variation,,,Resources.How,,,ToAll,,,How,,,ToChemicals,,,&,,,BioassaysDNA,,,&,,,RNAData,,,&,,,SoftwareDomains,,,&,,,StructuresGenes,,,&,,,ExpressionGenetics,,,&,,,MedicineGenomes,,,&,,,MapsHomologyLiteratureProteinsSequence,,,AnalysisTaxonomyTraining,,,&,,,TutorialsVariationAbout,,,NCBI,,,AccesskeysMy,,,NCBISign,,,in,,,to,,,NCBISign,,,Out;382(9891):507-515.Figure,,,4Randomised,,,trials,,,of,,,long-term,,,blood-pressure,,,lowering,,,for,,,secondary,,,stroke,,,prevention.Effects,,,of,,,Blood,,,Pressure,,,Targets,,,in,,,Patients,,,with,,,Recent,,,Lacunar,,,StrokeLancetAfter,,,,1,,,,year,,,,,mean,,,,systolic,,,,blood,,,,pressure,,,,was,,,,138,,,,mm,,,,Hg,,,,(95%,,,,CI,,,,137-139),,,,in,,,,the,,,,higher-target,,,,group,,,,and,,,,127,,,,mm,,,,Hg,,,,(95%,,,,CI,,,,126-128),,,,in,,,,the,,,,lower-target,,,,groupSBP=systolic,,,,blood,,,,pressure.Effects,,,,of,,,,Blood,,,,Pressure,,,,Targets,,,,in,,,,Patients,,,,with,,,,Recent,,,,Lacunar,,,,StrokeLancet 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